
FEMA 4774
CAS No. 1359963-68-0
FEMA 4774 ( S9632 )
产品货号. M22734 CAS No. 1359963-68-0
FEMA 4774 是 T1R2/T1R3 的正变构调节剂。 FEMA4774在感官评价测试中显示出明显的蔗糖甜度增强作用。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1191 | 有现货 |
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10MG | ¥1847 | 有现货 |
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25MG | ¥3467 | 有现货 |
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50MG | ¥5176 | 有现货 |
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100MG | ¥7209 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称FEMA 4774
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述FEMA 4774 是 T1R2/T1R3 的正变构调节剂。 FEMA4774在感官评价测试中显示出明显的蔗糖甜度增强作用。
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产品描述FEMA 4774 is a positive allosteric modulator of T1R2/T1R3.?FEMA4774 shows obvious enhancement of the sweetness of sucrose in sensory evaluation tests.
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体外实验FEMA 4774 (0-50 μM) induces a dose-dependent decrease in the EC50 value of sucrose and significantly enhances the affinity of sucrose for its binding site with an α (effect of modulator on agonist affinity) value of 30 in the human sweet receptor cells.
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体内实验FEMA 4774 (S9632) (oral gavage, 500-2000 mg/kg) does not cause a dose-dependent increase in polychromatic erythrocytes and induces micronuclei formation at dose levels up to 2000 mg/kg in Swiss albino (CD-1) mice.The pharmacokinetic parameters of FEMA 4774 (S9632) in Male and Female Sprague-Dawley Rats.
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同义词S9632
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通路Others
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靶点Other Targets
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受体T1R2/T1R3
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研究领域——
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适应症——
化学信息
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CAS Number1359963-68-0
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分子量359.45
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分子式C19H25N3O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : ≥ 41.67 mg/mL (115.94 )
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SMILESCC(C)NC(=O)C(C)(C)COc1cccc2nc(C)c(C(O)=O)c(N)c12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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