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FEMA 4774

CAS No. 1359963-68-0

FEMA 4774 ( S9632 )

产品货号. M22734 CAS No. 1359963-68-0

FEMA 4774 是 T1R2/T1R3 的正变构调节剂。 FEMA4774在感官评价测试中显示出明显的蔗糖甜度增强作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1191 有现货
10MG ¥1847 有现货
25MG ¥3467 有现货
50MG ¥5176 有现货
100MG ¥7209 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    FEMA 4774
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    FEMA 4774 是 T1R2/T1R3 的正变构调节剂。 FEMA4774在感官评价测试中显示出明显的蔗糖甜度增强作用。
  • 产品描述
    FEMA 4774 is a positive allosteric modulator of T1R2/T1R3.?FEMA4774 shows obvious enhancement of the sweetness of sucrose in sensory evaluation tests.
  • 体外实验
    FEMA 4774 (0-50 μM) induces a dose-dependent decrease in the EC50 value of sucrose and significantly enhances the affinity of sucrose for its binding site with an α (effect of modulator on agonist affinity) value of 30 in the human sweet receptor cells.
  • 体内实验
    FEMA 4774 (S9632) (oral gavage, 500-2000 mg/kg) does not cause a dose-dependent increase in polychromatic erythrocytes and induces micronuclei formation at dose levels up to 2000 mg/kg in Swiss albino (CD-1) mice.The pharmacokinetic parameters of FEMA 4774 (S9632) in Male and Female Sprague-Dawley Rats.
  • 同义词
    S9632
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    T1R2/T1R3
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1359963-68-0
  • 分子量
    359.45
  • 分子式
    C19H25N3O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : ≥ 41.67 mg/mL (115.94 )
  • SMILES
    CC(C)NC(=O)C(C)(C)COc1cccc2nc(C)c(C(O)=O)c(N)c12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

产品手册
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